The second apparition is alleged to have occurred a few years later. A lame boy would sell buttermilk to passing travelers, who would pause in the shade of a large Banyan tree, to escape the heat of the day. However, he had no customers. According to the account, suddenly, an ethereal woman, holding a child appeared before him, and asked for a cup of buttermilk. He gave her a cup, which she fed to her child. The woman asked the boy to go to Nagapattinam, and find a certain Catholic man in the town, and tell him to build a chapel at Vailankanni in her honor. Apparently cured, the boy ran to Nagapattinam, where he found the man and told him his story. The Catholic men of Nagapattinam subsequently built a thatched chapel at Vailankanni, dedicated to Mary under the title of "Our Lady of Good Health".

In the 17th century, a Portuguese merchant vessel sailing from Macau to Ceylon was caught in a severe storm in the Bay of Bengal. The sailors prayed fervently for Mary, Star of the Sea to save them, and promised to build a church in her honor wherever they could land. The sea became calm, and their ship landed near Vailankanni on 8 September, the Feast of the Nativity of Mary. To honor their promise, the Portuguese rebuilt the thatched chapel into a stone church. The church was later renovated twice in the early 20th century.

On August 21, 1879, a group of 15 men, women, and children, ranging in age from 5 to 75, reported seeing an apparition behind their church, against the back wall, of an altar with a lamb on it (understood to represent Jesus), surrounded by a multitude of angels. Off to the side in prayer stood Mary, Joseph, and St. John (with St. John dressed as a bishop). Because Mary was among those seen, the apparition is classified as Marian, although the simultaneous appearance of Jesus, Mary, Joseph, John, and numerous angels makes it unique among this category. A further distinctive characteristic is that this apparition was silent: no verbal messages were given. The apparition lasted for an hour and a half.^[22]

If men do not repent and better themselves, the Father will inflict a terrible punishment on all humanity. It will be a punishment greater than the deluge, such as one will never have seen before. Fire will fall from the sky and will wipe out a great part of humanity, ... the good as well as the bad, sparing neither priests nor faithful. The survivors will find themselves so desolate that they will envy the dead. The only arms which will remain for you will be the Rosary and the Sign left by My Son. Each day recite the prayer of the Rosary. With the Rosary pray for the Pope, bishops and the priests. The work of the devil will infiltrate even into the Church in such a way that one will see cardinals opposing cardinals, and bishops against other bishops.^[65]

In 1956, the bishop of Haarlem "found no evidence of the supernatural nature of the apparitions",^{[note 3]} a judgment which the Congregation for the Doctrine of the Faith (CDF) confirmed in 1974.^[104] Nevertheless, two decades later, the CDF gave Bishop Bomers permission to authorize public veneration of the title, image, and prayer associated with the apparition, which he did in 1996.^[100] In 2002, Bishop Punt took the further step of declaring the apparitions themselves to be approved, despite the CDF's previous ruling on the question. In 2020, Bishop Hendriks, in consultation with the CDF, reiterated that the CDF's unfavorable judgment stands, and that the veneration of the associated title, image, and prayer cannot be construed as endorsement of the apparition itself.^[101][102]