Asad ibn Abd al-Uzza (Arabic: أسد بن عبدالعزى, romanized: Asad ibn ʿAbd al-ʿUzzā) was a grandson of Qusai ibn Kilab and the matrilineal great-great-grandfather of the prophet of Islam Muhammad.

He was the son of Abd al-Uzza ibn Qusai and the father of Umm Habib bint Asad, who was the mother of Barrah bint Abdul Uzza, who was the mother of Aminah bint Wahb, who was the mother of Muhammad.^[1]

Asad is the eponym ancestor of the Quraysh Banu Asad tribe. He probably had many daughters and sons. But his only known daughter is Umm-Habib bint-Asad the mother of Barra, who married Wahb of the Quraysh Banu Zuhra tribe whose mother is said to have been named `Atiqa. More importantly, Barra is the mother of Amina bint-Wahb, who is Muhammad`s mother. This means that following Muhammad`s maternal lineage, one finds that Asad is the fourth-generation ascendant of Muhammad. Asad`s only know son is Nawfal bin-Asad although he probaby had many other children (daughters and sons). Nawfal's known sons are Waraqa bin-Nawfal and Khuwaylid bin-Nawfal. The major islamic biographical sources such as ibn-Hisham (basing his assertion of the so-called ibn-Ishaq biography which actually never existed), wrongly mention Waraqa as being Asad's son and not Asad's grandson (e.g. Nawfal's son). As for Khuwaylid, he had four known children: Nawfal bin-Khuwaylid, Khadidja bint-Khuwaylid who will become the first wife of Muhammad, Hala bint-Khuwaylid who will become the wife of Kayruz ibn-al-Rabi` (known by his konya Abu-l-`As), and al-`Awwam bin-Khuwaylid who will marry Safiyya bint-`Abd-al-Muttalib who is the aunt of Muhammad (yet younger than him) and the sister of Hamza bin-`Abd-al-Muttalib Muhammad's uncle, reminding though that both Safiyya and Hamza were younger than Muhammad.

• Muhammad son of Aminah bint Wahb daughter of Barrah bint Abdul Uzza daughter of Umm Habib bint Asad daughter of Asad ibn `Abd al-`Uzza
• Khadijah bint Khuwaylid daughter of Khuwaylid ibn Asad son of Asad ibn `Abd al-`Uzza

The Zubayrids branch which descended from Zubayr ibn al-Awwam, an important member of Asadi clan, were an important faction during the Second Fitna, the second early Islamic civil war. After Mu'awiya declared his son Yazid to be his successor, Zubayr's son Abd Allah refused to acknowledge Yazid as the caliph in 676.^[2] In 683, Abd Allah gained control of Mecca and established a polity. After Yazid's death, Abdullah declared himself the Amir al-Mu'minin (Commander of the Believers) and founded the Zubayrid Caliphate. Soon after, Abd Allah gained control of half of Persia as well as half of Egypt. Both the Alids (family and descendants of Ali, fourth Rashidun caliph) and the Zubayrids were two of the Companions of the Prophet dynasties which held the most numerous lands and estates within caliphate realm.^[3]

The Zubayrids regime were fond to appoint peoples with Yemeni Azd background as governors in al-Sham subunits.^[4] This included southern clans of Kinda and Kalb.^[4]