As leader of the Ambazonia Governing Council, Ayaba and Chairman Benedict Kuah oversaw the creation of the Ambazonia Defence Forces, which carried out its first guerilla action on September 9, 2017. This was the first armed action by Ambazonian separatists in what would become known as the Anglophone Crisis.[11] This happened seven weeks before the Interim Government of Ambazonia was established, and months before it endorsed an armed struggle.[12]
The AGC's relationship with the Interim Government was oftentimes strained. In March 2019, Ayaba refused to attend the All Southern Cameroons People's General Conference in Washington, D.C., calling some of the attendants "enablers". The AGC did thus not become part of the Southern Cameroons Liberation Council.[13] During the 2019 Ambazonian leadership crisis, Ayaba supported Sisiku Julius Ayuk Tabe against Samuel Ikome Sako "out of principle". Ayaba argued that it was wrong to attack Ayuk Tabe, who had been under detention since January 2018.[14]
In July 2019, Ayaba claimed that Cameroon had practically lost the war, and that separatist forces controlled 80 percent of the Anglophone regions.[15]
On April 9, 2021, Ayaba held a joint press conference with Nnamdi Kanu, leader of the Indigenous People of Biafra (IPOB), where they declared an alliance between Biafra and Ambazonia.[16] Ayaba has also proposed an alliance with democratic forces within Cameroon, proposing that Ambazonia should help overthrow Paul Biya.[17]
In March 2022, Ayaba Lucas Cho presented himself, on his Twitter page, as the sponsor of the terrorist attack of Ekondo Titi, which caused the death of seven people, including the sub-prefect and the mayor of this city. in the South West region of Cameroon.[18]
