Originally ran from the A5 in Valley to the B5111 on the western side of Amlwch. Upgraded to an extension of the A5025 by the end of the 1920s. The final section into Amlwch was renumbered to the B5111 in the 1940s.

Number also appears in the DfT Card Index from around 2002 on a route along Record Street in Ruthin, but no maps showing the route as a B road have been found.

Originally ran from the A525 in Rhuddian to the A548 near Gronant. The section from Gronant to Prestatyn became an extension of the A548 by 1932 and the remainder was renumbered as an extension of the A547 in the 1950s.

Originally from the A494 King Street to the A549 Chester Street in Mold. Downgraded by the end of World War II; the southern section is now part of the A541, but the remainder is unclassified.

Originally ran from the A494 north of Mold to the A548 in Flint. Due to its importance, it was upgraded to Class I status as the A5119 after World War II.

Originally ran from the A5119 south of Northop to the High Street in Northop. Declassified after the A55 North Wales Expressway was built.

Originally ran from the A5047 at Broad Green to the A562 at Penketh (now part of Warrington). Upgraded to Class I status as the A5080 by 1932.

Originally ran along Victoria Street in Liverpool. Now unclassified, although some maps show the eastern end still as the B5181.

Originally ran from the B5213 in Stretford to the B5217 in Chorlton cum Hardy; the western end is now part of the B5213 and the remainder upgraded to the A5145.

The number also appears in the DfT Card Index from around 2002 as a route along Long Street in Wigston. There is no evidence (apart from a single unofficial online reference) that the number was used for this route; official documents in 1978 and 2013 state the route as a portion of the B5418. The same reference also states that Paddock Street was a portion of the B5216, but this was a cul-de-sac before 1978 and is also odd that the number would have changed between 1978 and 2013.

Originally ran along Corporation Street in Preston; became a portion of a rerouted A59. After the A59 was rerouted, the section north of Ringway became a portion of the A5071 and the southern portion downgraded to the C329.

First used along the southernmost section of Devonshire Road in Blackpool. Became a portion of a rerouted A587 by 1932 (old A587 became an unnumbered Class II road, although the two routes may have swapped numbers in the 1920s). After the A587 returned to its original routing to form a portion of the Blackpool eastern bypass, this became a portion of the B5124.

Next used along Bispham Road in Blackpool from the A587 to the A586, along the old route of the A587 (which was rerouted over the original B5264). Returned to the A587 after it was routed back to its original route; the old route of the A587 (the original B5264) is now the B5124. The OS maps show the last bit along Benson Road and the final part along Bispham Road as part of the B5264, despite it not showing on any other maps nor signed on the ground.

Originally ran from the A590 in Greenodd to the A593 in Torver. Upgraded to Class I status as the A5084 in the mid-1920s; the southern section is now part of the A5092.

First used from the A592 at Glencoyne Park to the A594 (now A66) in Troutbeck. This was upgraded to Class I status as the A5091 in the mid-1920s.

Next used from the then-B5320 just outside Stainton to the then-A594 at Penruddock, paralleling the current route. Became a portion of the A66 in 1968 after the M6 Penrith bypass opened.

May also have been used along the now-A5103 Princess Parkway/Princess Road in Manchester, as the 1932 and 1933 OS Ten Mile road maps show the number running through southern Manchester to the A560 on the southwest side of Northenden (now in Wythenshawe). The route is shown as the B529 (a typo) on a 1934 map. The 1934 OS Ten Mile map shows the route as upgraded to the A5103 and the B5290 along its current route near Lancaster.

First used from the B5292 in Cockermouth to the A595 near Egremont. Due to its importance, it was upgraded early on to Class I status as the A5086 in the mid-1920s.

Next used from the B5992 in Low Lorton to Buttermere. Became an extension of the B5289 in 1935.

Originally ran from the A595 in Papcastle to the A596 near Maryport. Renumbered as an extension of the A594 in the 1920s.

Originally ran along Brunswick Road in Penrith; renumbered as a portion of the A592 in 1968 after the M6 Penrith bypass was built.

Also appeared in the DfT Roads List as a route along Woolston Grange Avenue between the A57 and A574 east of Warrington, but this is a typo for the B5210.

First used in 1924 along Finkle Street and Corporation Road in Carlisle. Upgraded to a spur of the A595 in the 1940s, although a portion has been bypassed. Next used as an inner relief road into Lichfeld; one portion was upgraded to the A5127 and the remainder declassified.

Originally ran along Park Street and Kinsey Street in Congleton, now unclassified and split up by the A54 relief road.

Originally ran along New Park Road in Salford; was the A5065 before it was downgraded between 1960 and 1975. Now unclassified; some of the route is gone, part of the park or due to redevelopment.

Originally ran west of Swadlincote from the B586 to the A511 (now A444). Both B5358s are shown on a 1932 map; this could be a map error, or both routes actually coexisted for some time. Whatever the result, this B5358 is now the B5353.

Originally a short loop off the A594 in Keswick. The sections along Victoria Street and Bank Street are now part of the A5271 (they were the A594 before this).

Originally the first section of Derby's outer ring road, between the A516 and A514. Extended and renumbered in the late 1930s to the A5111.

Originally ran from St Asaph to Trefnant. Renumbered to a portion of the B5381 in 1935, then a portion of a rerouted A525, and is now back to the B5381.

Originally ran along Westfield Road in Wellingsborough; was formerly the B573. Now declassified.

Originally ran from the B5366 in Aylestone to the A50 (now A5199) in Wigston Magna; this is now part of an extended B5418.