Beta-apo-4'-carotenal_oxygenase

Beta-apo-4'-carotenal oxygenase

Beta-apo-4'-carotenal oxygenase

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Beta-apo-4'-carotenal oxygenase (EC 1.2.1.82, beta-apo-4'-carotenal dehydrogenase, YLO-1, carD (gene)) is an enzyme with systematic name 4'-apo-beta,psi-carotenal:NAD+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction:

4'-apo-beta, psi-caroten-4'-al + NAD+ + H2O neurosporaxanthin + NADH + 2 H+
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Neurosporaxanthin is responsible for the orange color of Neurospora.

References

  1. [1]
    Estrada AF, Youssar L, Scherzinger D, Al-Babili S, Avalos J (September 2008). "The ylo-1 gene encodes an aldehyde dehydrogenase responsible for the last reaction in the Neurospora carotenoid pathway". Molecular Microbiology. 69 (5): 1207–20. doi:10.1111/j.1365-2958.2008.06349.x. PMID 18627463.
  2. [2]
    Díaz-Sánchez V, Estrada AF, Trautmann D, Al-Babili S, Avalos J (September 2011). "The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi". The FEBS Journal. 278 (17): 3164–76. doi:10.1111/j.1742-4658.2011.08242.x. PMID 21749649.
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