Blaine County is a county in the U.S. state of Nebraska. As of the 2020 United States Census, the population was 431,^[1] making it Nebraska's second-least populous county and the sixth-least populous in the United States. Its county seat is Brewster.^[2] The county was formed in 1885^[3] and organized in 1886.^[4] It is named after presidential candidate James G. Blaine.^[5]

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Blaine County
County
Blaine County Courthouse in Brewster
Location within the U.S. state of Nebraska
Nebraska's location within the U.S.
Coordinates: 41°56′N 99°59′W
Country	United States
State	Nebraska
Founded	1885 (authorized) 1886 (organized)
Named for	James G. Blaine
Seat	Brewster
Largest village	Dunning
Area
• Total	714 sq mi (1,850 km2)
• Land	711 sq mi (1,840 km2)
• Water	3.6 sq mi (9 km2)  0.5%
Population  (2020)
• Total	431
• Density	0.60/sq mi (0.23/km2)
Time zone	UTC−6 (Central)
• Summer (DST)	UTC−5 (CDT)
Congressional district	3rd
Website	blainecounty.nebraska.gov

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In the Nebraska license plate system, Blaine County is represented by the prefix 86 (it had the 86th-largest number of vehicles registered in the state when the license plate system was established in 1922).

According to the US Census Bureau, the county has an area of 715 square miles (1,850 km²), of which 711 square miles (1,840 km²) is land and 3.6 square miles (9.3 km²) (0.5%) is water.^[6]

As of the 2000 United States Census,^[12] there were 583 people, 238 households, and 168 families in the county. The population density was 0.82 person per square mile (0.32 person/km²). There were 333 housing units at an average density of 0.5 units per square mile (0.19/km²). The racial makeup of the county was 98.97% White, 0.51% Native American, and 0.51% from two or more races; 0.17% of the population were Hispanic or Latino of any race. 45.1% were of German, 12.2% English, 10.2% Irish and 8.4% American ancestry.

There were 238 households, of which 30.30% had children under the age of 18 living with them, 66.00% were married couples living together, 2.50% had a female householder with no husband present, and 29.00% were non-families. 26.90% of all households were made up of individuals, and 13.90% had someone living alone who was 65 years of age or older. The average household size was 2.45 and the average family size was 2.98.

The county population contained 26.20% under the age of 18, 3.90% from 18 to 24, 26.60% from 25 to 44, 26.40% from 45 to 64, and 16.80% who were 65 years of age or older. The median age was 40 years. For every 100 females there were 101.70 males. For every 100 females age 18 and over, there were 100.90 males.

The median income for a household in the county was $25,278, and the median income for a family was $28,472. Males had a median income of $17,917 versus $20,000 for females. The per capita income for the county was $12,323. About 18.70% of families and 19.40% of the population were below the poverty line, including 21.70% of those under age 18 and 9.40% of those age 65 or over.

Blaine County voters are strongly Republican. In only four national elections since 1900 has the county selected the Democratic Party candidate, & none since 1936.