Nashville Predators

Leipsic was selected by the Nashville Predators in the third-round (89th overall) of the 2012 NHL Entry Draft.^[1] On May 23, 2013, the Predators signed Leipsic to a three-year entry-level contract.^[12]

Leipsic was assigned to the Predators AHL affiliate, the Milwaukee Admirals to begin his first professional season in 2014–15. He led the Admirals in rookie scoring with 36 points in 47 games.

Toronto Maple Leafs

On February 15, 2015, the Predators traded Leipsic along with Olli Jokinen and Nashville's 2015 first round draft pick to the Toronto Maple Leafs in a package deal for Cody Franson and Mike Santorelli.^[13] Leipsic played an important role down the stretch in helping the Toronto Marlies (a team that struggled to score early in the year) reach the post-season.

Leipsic began the 2015–16 season with the Marlies, and would play there for most of the year. However, in February 2016, the Maple Leafs lineup was depleted due to injuries. Wanting to allow younger players to remain in the AHL and develop, Toronto initially called up older veterans.

When injury struck again however, Leipsic was called up on February 13, 2016, in reward for his strong play, along with Jeremy Morin, both on an emergency basis.^[14] Leipsic made his debut the same night, in a road game against the Vancouver Canucks, and scored his first NHL goal midway through the second period, batting a flying puck out of mid-air and past goaltender Ryan Miller.^[15] The reaction of Leipsic's parents, who were in attendance and flew last minute to the game, garnered much media attention.^[15] Leipsic became the first Maple Leafs' player to score a goal in his NHL debut since Nikolay Kulemin in 2008. Leipsic was sent back to the Marlies shortly after his debut.

Vegas Golden Knights

On June 21, 2017, Leipsic was left exposed at the 2017 NHL Expansion Draft by the Toronto Maple Leafs, and was selected by the Vegas Golden Knights.^[16] He signed a two-year $1.3 million contract in July 2017.^[17]

Vancouver Canucks

On February 26, 2018, Leipsic was traded to the Vancouver Canucks in exchange for Philip Holm.^[18]

Los Angeles Kings

In the 2018–19 season, on December 3, 2018, Leipsic was placed on waivers by the Canucks and claimed by the Los Angeles Kings.^[19]

Washington Capitals

Leipsic was not tendered a qualifying offer by the Kings and was released as a free agent on June 25, 2019.^[20] He was signed by the Washington Capitals to a one-year, $700,000 contract on July 1, 2019.^[2] In the 2019–20 season, Leipsic remained on the Capitals roster for opening night. In a depth forward role, Leipsic registered 3 goals and 8 assists for 11 points in 61 games, before the season was suspended due to the COVID-19 pandemic.

HC CSKA Moscow

Leipsic’s contract with the Capitals was terminated in May 2020 due to a disrespectful private group chat was leaked in which he insulted women and his teammates. Leipsic opted to resume his career by agreeing to a one-year contract with the Russian club, HC CSKA Moscow of the KHL, on August 4, 2020.^[21] In the 2020–21 season, he posted 11 goals and 24 points in 42 regular season games along with 8 points in 16 playoff games.

Metallurg Magnitogorsk

On May 7, 2021, Leipsic was traded by CSKA to Metallurg Magnitogorsk in exchange for the rights to Lias Andersson, and immediately signed a two-year contract with the club. He participated in the 2021–22 playoffs, despite the exit of many North American-born players and two of the KHL's non-Russia-based teams due to the 2022 Russian invasion of Ukraine.^[22]

SKA Saint Petersburg

On June 23, 2023, Leipsic continued his tenure in the KHL by signing as a free agent to a two-year contract with SKA Saint Petersburg.^[23]