Brescia or da Brescia is a surname derived from the city of Brescia in Italy. Notable people with the surname include:

• Alfonso Brescia (1930–2001), film director
• Domenico Brescia (1866–1939), composer
• Fortunato Brescia Tassano (d. 1951), Italian-born Peruvian businessman
• Georgia Brescia (born 1996), Italian tennis player
• Giovanni Antonio da Brescia, Italian painter
• Giovanni Maria da Brescia, Italian painter
• Jason Michael Brescia (born 1986), American comedy writer-director
• Justin Brescia (born 1982), American actor
• Leonardo Brescia (1520–1582), Italian painter
• Lisa Brescia (born 1970), American actress
• Mario Brescia Cafferata (1929–2013), Peruvian billionaire businessman
• Moretto da Brescia (c. 1498–1554), Italian painter
• Pedro Brescia Cafferata (1921–2014), Peruvian businessman
• Rosa Brescia Cafferata (born c. 1926), Peruvian billionaire heiress and philanthropist

This page lists people with the surname Brescia.
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