Charles Edward "Buzz" Wetzel (August 25, 1894 – March 7, 1941) was a pitcher in Major League Baseball who played briefly for the Philadelphia Athletics during the 1927 season. Listed at 6 ft 1 in (1.85 m), 162 lb., Wetzel batted and threw right-handed. He was born in Jay, Oklahoma.

Wetzel was 32 years old when he entered the majors on July 27, 1927, and did not have a decision or strikeouts. Wetzel posted a 7.71 earned run average in two games, including one start, giving up four earned runs on eight hits and five walks in 4+2⁄3 innings of work. As a hitter, he went 1-for-1 with a run scored. He pitched his final game on July 28, and never appeared in a major league game again.

Following his majors career, Wetzel pitched and managed in the minor leagues. Wetzel died in Globe, Arizona, at the age of 46.

• Career statistics and player information from Baseball Reference, or Baseball Reference (Minors)
• Retrosheet

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