CARD8

Caspase recruitment domain-containing protein 8

Caspase recruitment domain-containing protein 8

Protein found in humans

Caspase recruitment domain-containing protein 8 is a protein that in humans is encoded by the CARD8 gene.[3][4][5]

Quick Facts CARD8, Available structures ...

Function

Caspase recruitment domain (CARD)-containing proteins, such as CARD8, are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NF-κB) in the context of apoptosis or inflammation, respectively.[5]

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000105483 – Ensembl, May 2017
  2. [2]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. [3]
    Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jul 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.
  4. [4]
    Pathan N, Marusawa H, Krajewska M, Matsuzawa S, Kim H, Okada K, Torii S, Kitada S, Krajewski S, Welsh K, Pio F, Godzik A, Reed JC (Aug 2001). "TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer". J Biol Chem. 276 (34): 32220–9. doi:10.1074/jbc.M100433200. PMID 11408476.
  5. [5]
    "Entrez Gene: CARD8 caspase recruitment domain family, member 8".

Further reading


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