Charlie, Charley or Charles Chase may refer to:

• Charles L. Chase (1828—after 1877), American politician from Minnesota
• Charles A. Chase (1864–1937), American tennis champion
• Charley Chase (1893–1940), American comedy actor, screenwriter and film director
• Charles Chase (boxer) (1931–1997), Canadian Olympic light middleweight
• Charlie Chase (broadcaster) (born 1952), American radio and television host (Crook & Chase)
• DJ Charlie Chase (born 1959), American DJ; key supporter of Puerto Rican music and culture

• Charlie Hall Chase, English horse race established in 1969

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