Conrail acquired the line in 1976, and later sold some of it to the Norfolk Southern Railway to relieve that company's ex-Nickel Plate Road main line. CSX Transportation acquired the entire line in the 1999 breakup of Conrail, and began to make improvements, including new crossing signals, paving crossings, and weeding the railroad. After this was complete, signs were posted at each crossing notifying motorists of an increase in train traffic.
In 2004, operations under the Chicago, Ft. Wayne & Eastern Railroad name began; from the beginning of operations, the railroad has been owned by RailAmerica.[3]
In 2011 former Norfolk Southern supervisor Joseph (Joe) Parsons was named the General Manager of Chicago, Fort Wayne, & Eastern Railroad headquartered in Fort Wayne, Indiana.
On July 23, 2012, Genesee & Wyoming Inc. announced that it intended to purchase RailAmerica in a deal valued at $1.39 billion.[4][5] Approval of the purchase was granted by the U.S. Surface Transportation Board on December 19, 2012,[6] and ownership of the Chicago, Ft. Wayne & Eastern was transferred to the G&W.
As of 2023, there are many interchanges in CFE:
BNSF (Chicago, Illinois); Belt Railway of Chicago (Chicago, Illinois); Canadian National (Chicago, Illinois); CPKC (Chicago, Illinois); Chicago Rail Link (Chicago, Illinois); Chicago South Shore & South Bend Railroad (Chicago, Illinois); CSX (Crestline, Ohio and Lima, Ohio); Gary Railway (Chicago, Illinois); Iowa Interstate Railroad (Chicago, Illinois); Indiana Harbor Belt Railroad (Chicago, Illinois); Indiana & Ohio Railway (Lima, Ohio); Manufacturers' Junction Railway (Chicago, Illinois); Norfolk Southern (Fort Wayne, Indiana and Lima, Ohio); South Chicago and Indiana Harbor Railway (Chicago, Illinois); Union Pacific (Chicago, Illinois); Wisconsin and Southern Railroad (Chicago, Illinois). [7]