Citrate_CoA-transferase

Citrate CoA-transferase

Citrate CoA-transferase

Class of enzymes

In enzymology, a citrate CoA-transferase (EC 2.8.3.10) is an enzyme that catalyzes the following chemical reaction:

acetyl-CoA + citrate acetate + (3S)-citryl-CoA
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Thus, the two substrates of this enzyme are acetyl-CoA and citrate, whereas its two products are acetate and (3S)-citryl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is acetyl-CoA:citrate CoA-transferase. This enzyme participates in citrate cycle (tca cycle).

References

    • Dimroth P, Loyal R, Eggerer H (1977). "Characterization of the isolated transferase subunit of citrate lyase as a CoA-Transferase. Evidence against a covalent enzyme-substrate intermediate". Eur. J. Biochem. 80 (2): 479–88. doi:10.1111/j.1432-1033.1977.tb11903.x. PMID 336371.


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