The Club Deportivo Universidad Católica is a multi-sports organization from Chile representing the Pontificia Universidad Católica de Chile that puts together 14 sport branches, being the most famous the football branch. The club has the best infrastructure in the country and has the most sport branches than any other club. Until the soccer branch became independent a few years ago, it was this branch that shared its earnings with the other branches, allowing them to survive and succeed. However, these actions prevented the soccer club to reinvest and compete aggressively at the domestic and international level, where there are other clubs with bigger budgets and funds to invest in players.

Since its foundation, the colors that identify the team are the white and the blue. While in their club's logo you can see these same colors with red, besides representing it with a cross, showing the club's Catholic character.

The club's foundation was in 1908. Even though the sports activities in the university began years before, the idea from Raúl Agüero in 1925 to gather sport activities from the university under the same name was the beginning of the formation of what became the Club Deportivo Universidad Católica. This way, it began to act as an organized identity and totally dependent from the university on 30 August 1927, when the then director, Monseñor Carlos Casanueva obtained the permits to use Campos de Sports de Ñuñoa for the sporting activities of the university.

It began its participation in the University Confederation of sports in 1928, participating together with the Universidad de Concepción, the Universidad Católica de Valparaíso and the Universidad de Chile.

On 19 April 1937 the university joins the Chilean Football Association. Because of this, a group of students from the university, got together in a house of studies in Santiago de Chile on 21 April 1937 to discuss the organization of the club. This would become the official date of foundation.

The football branch made its official debut on 13 June 1937 in the then Segunda División of Chilean professional football, in a game against Universidad de Chile, the longtime rival of the club, in the military stadium.

In the beginning part of the 1980s, it began the migration of some sporting branches to the Sporting complex named San Carlos de Apoquindo.

• 1937–1938: Augusto Gómez Soto
• 1939–1946: Jimmy Rasmusen Bowden
• 1947–1949: Óscar Álvarez Lon
• 1950–1951: Enrique Casorzo Federici
• 1952–1953: Alejandro Duque Lagos
• 1953–1954: Carlos Dittborn Pinto
• 1954–1955: Sergio Urrejola Rozas
• 1955–1956: Enrique Casorzo Federici
• 1957–1965: Eduardo Cuevas Valdés
• 1966–1967: Enrique Casorzo Federici
• 1968–1974: Manuel Vélez Samaniego
• 1975–1976: Raúl Devés Jullian
• 1976–1977: José Martínez Guichou
• 1978–1982: Germán Mayo Correa
• 1982–1993: Alfonso Swett Saavedra
• 1994–1996: Jorge Claro Mimica
• 1996–1998: Manuel Vélez Samaniego
• 1999–: Jorge O´Ryan Schütz

Its lyrics were written by Pedro Fornazzari, Charles Bown and Alberto Buccicardi, the two last were ex players from the club and directors of the magazine revista Estadio.

Emulating the melody used by the supporters of the British club Manchester United, they gave birth to the Anthem of the institution, immortalizing the phrase "Por la Patria, Dios y la Universidad", which translates to "For the country, God and the University".

The first stadium that belonged to the university was the Estadio Independencia, opened 14 October 1945.

Years later, the municipality of Las Condes gave, for 99 years, some land located in Santa Rosa, that later on became known as the Santa Rosa de Las Condes Sport complex.

In 1971 the club lost its stadium due to the poor economic situation of the university.

In 1972 it was introduced the first project for a new stadium, that ended up in the opening on 4 September 1988 of the Estadio San Carlos de Apoquindo.