Coat protein may refer to:

• Viral coat protein, a component of the capsid
• Variable surface glycoproteins or procyclins, surface coat proteins of either the bloodstream form or the procyclic form of the parasite Trypanosoma brucei
• COPI, a type of vesicle coat protein that transports proteins from the cis end of the Golgi complex back to the rough endoplasmic reticulum
• COPII, a type of vesicle coat protein that transports proteins from the rough endoplasmic reticulum to the Golgi apparatus

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