Cobra_venom_factor-dependent_C3_convertase

Alternative-complement-pathway C3/C5 convertase

Alternative-complement-pathway C3/C5 convertase

Add article description

Alternative-complement-pathway C3/C5 convertase (EC 3.4.21.47, complement component C3/C5 convertase (alternative), proenzyme factor B, properdin factor B, C3 proactivator, glycine-rich beta-glycoprotein, heat-labile factor, C3 convertase, C3b,Bb,CVF,Bb,C5 convertase, (C3b)n,Bb, complement C 3(C 5) convertase (amplification), alternative complement pathway C3(C5) convertase, C5 convertase, CVF,Bb, (CVF)-dependent glycine-rich-beta-glucoprotein, cobra venom factor-dependent C3 convertase) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Cleavage of Arg-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg- bond in complement component C5 alpha-chain to yield C5a and C5b
Quick Facts Identifiers, EC no. ...

This enzyme is a bimolecular complex of complement fragment Bb with either C3b or cobra venom factor.

See also

References

  1. [1]
    Kerr MA (1981). "[8] Human factor B". Human factor B. Methods in Enzymology. Vol. 80 Pt C. pp. 102–12. doi:10.1016/s0076-6879(81)80010-9. ISBN 9780121819804. PMID 7043188.
  2. [2]
    Morley BJ, Campbell RD (January 1984). "Internal homologies of the Ba fragment from human complement component Factor B, a class III MHC antigen". The EMBO Journal. 3 (1): 153–7. doi:10.1002/j.1460-2075.1984.tb01776.x. PMC 557312. PMID 6323161.
  3. [3]
    Müller-Eberhard HJ (1988). "Molecular organization and function of the complement system". Annual Review of Biochemistry. 57: 321–47. doi:10.1146/annurev.bi.57.070188.001541. PMID 3052276.
Share this article:

This article uses material from the Wikipedia article Cobra_venom_factor-dependent_C3_convertase, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.