The Communist Party of Khorezm (Persian: حزب کمونیست خوارزم; Uzbek: Xorazm Kommunistik partiyasi) was a political party in the final months of the Khanate of Khiva, and after 26 April 1920 the Khorezm People's Soviet Republic.

In 1922, the party became affiliated to the Russian Communist Party (Bolsheviks). During the spring of 1924, when proposals for reorganization of Soviet Central Asia were discussed the leadership of the Communist Party of Khorezm declined to take any firm position on the issue. Only in July the same year did the party formally approve of the plans to form Soviet republics on nationality-based boundaries. The official Soviet histography at the time claimed that the Communist Party of Khorezm had been a nest of "bourgeois-and-nationalistic and Trotskyist elements, who hampered the forming of new Republics".^[2] Later, in 1924, the party was dissolved as the boundaries of Soviet Central Asia were redrawn, with the Khorezm SSR being split between the Uzbek and Turkmen SSRs and the Karakalpak Autonomous Oblast.

There were nine leaders of the party during its four-year existence:^[3]