The Coptic Catholic Eparchy of Giza is an Eastern Catholic diocese in Giza. It is one of the suffragan sees comprising the sole ecclesiastical province (covering all Egypt) of the Coptic Catholic Patriarch of Alexandria, the head of the Coptic Catholic Church, a Particular church sui iuris (Alexandrian Rite).

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Its episcopal see is Saint George cathedral in Giza, which is part of the national capital Cairo's metropolitan area.

As per 2014, it pastorally served 5,940 Coptic Catholics in 9 parishes with 13 priests (12 diocesan, 1 religious), 70 lay religious (22 brothers, 48 sisters) and 4 seminarians.

Established on 21 March 2003 as Eparchy (Eastern Catholic Diocese) of Giza(–Fayoum–Beni Souef) / Gizen(sis) (Latin adjective), on territory split off from the Coptic Catholic Patriarchate of Alexandria's proper diocese, as its suffragan.

(all Coptic Alexandrian Rite)

Suffragan Eparchs (Bishops) of Giza (Guizeh)

• Andraos Salama (21 March 2003 – 6 December 2005), Titular Bishop of Barca (1 November 1988 – 21 March 2003) as Auxiliary Bishop of the Patriarchate Alexandria of the Copts (Egypt) (1 November 1988 – death 1997)
• Antonios Aziz Mina (3 January 2006 – retired 23 January 2017), previously Titular Bishop of Mareotes (21 December 2002 – 3 January 2006) as Bishop of Curia of the Copts ([19 December 2002] 21 December 2002 – 3 January 2006)
• Apostolic Administrator Ibrahim Isaac Sedrak (23 January 2017 – ...), while Patriarch of Alexandria of the Copts (Egypt) ([15 January 2013] 18 January 2013 – ...), also President of Synod of the Catholic Coptic Church (15 January 2013 – ...) and President of Assembly of the Catholic Hierarchy of Egypt (15 January 2013 – ...); previously Eparch (Bishop) of Minya of the Copts (Egypt) ([29 September 2002] 5 October 2002 – 15 January 2013).

• List of Catholic dioceses in Egypt