D-aspartate_oxidase

D-aspartate oxidase

D-aspartate oxidase

Class of enzymes

Not to be confused with D-amino acid oxidase or Diamine oxidase.

In enzymology, a D-aspartate oxidase (EC 1.4.3.1) is an enzyme that catalyzes the chemical reaction

D-aspartate + H2O + O2 oxaloacetate + NH3 + H2O2
Quick Facts Identifiers, EC no. ...

The 3 substrates of this enzyme are D-aspartate, H2O, and O2, whereas its 3 products are oxaloacetate, NH3, and H2O2.

This enzyme belongs to the FAD dependent oxidoreductase family, specifically those acting on the CH-NH2 group of donors with oxygen as acceptor. The systematic name of this enzyme class is D-aspartate:oxygen oxidoreductase (deaminating). Other names in common use include aspartic oxidase, and D-aspartic oxidase. This enzyme participates in alanine and aspartate metabolism. It employs one cofactor, FAD.

The enzyme is encoded by DDO gene.

See also

References

    • Dixon M, Kenworthy P (1967). "D-aspartate oxidase of kidney". Biochim. Biophys. Acta. 146 (1): 54–76. doi:10.1016/0005-2744(67)90073-3. PMID 6060479.
    • Still JL, Buell MV, Knox WE, Green DE (1949). "Studies on the cyclophorase system. VII. D-Aspartic oxidase". J. Biol. Chem. 179: 831–837.
    • Still JL; Sperling E (1950). "On the prosthetic group of the D-aspartic oxidase". J. Biol. Chem. 182: 585–589.


    This EC 1.4 enzyme-related article is a stub. You can help Wikipedia by expanding it.
    Share this article:

    This article uses material from the Wikipedia article D-aspartate_oxidase, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.