D-ribitol-5-phosphate_cytidylyltransferase

D-ribitol-5-phosphate cytidylyltransferase

D-ribitol-5-phosphate cytidylyltransferase

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In enzymology, a D-ribitol-5-phosphate cytidylyltransferase (EC 2.7.7.40) is an enzyme that catalyzes the chemical reaction

CTP + D-ribitol 5-phosphate diphosphate + CDP-ribitol
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Thus, the two substrates of this enzyme are CTP and D-ribitol 5-phosphate, whereas its two products are diphosphate and CDP-ribitol.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is CTP:D-ribitol-5-phosphate cytidylyltransferase. Other names in common use include CDP ribitol pyrophosphorylase, cytidine diphosphate ribitol pyrophosphorylase, ribitol 5-phosphate cytidylyltransferase, and cytidine diphosphoribitol pyrophosphorylase. This enzyme participates in pentose and glucuronate interconversions.

References

    • Shaw DR (February 1962). "Pyrophosphorolysis and enzymic synthesis of cytidine diphosphate glycerol and cytidine diphosphate ribitol". The Biochemical Journal. 82: 297–312. PMC 1243453. PMID 13911452.


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