DOS 8 or DOS-8 may refer to:

• DR-DOS 8.0, a version of DR-DOS distributed by DeviceLogics in 2004
• MS-DOS 8.0, the MS-DOS sub-system bundled in Microsoft Windows ME in 2000
• DOS-8 a.k.a. Mir-2, Russian spacecraft project of Salyut program in 2000
• Zvezda (ISS module), the final destination of the Russian DOS-8 module

• 86-DOS
• DOS (disambiguation)
• DOS 7 (disambiguation)
• DOS 10 (disambiguation)

This disambiguation page lists articles associated with the same title formed as a letter–number combination.
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