The Depayin massacre (Burmese: ဒီပဲယင်း လူသတ်မှု) occurred on 30 May 2003 in Tabayin (Depayin), a town in Myanmar's Sagaing Division (now Sagaing Region), when at least 70 people associated with the National League for Democracy were killed by a government-sponsored mob.^[1][2][3] In an April 2012 interview, Khin Nyunt, formerly the country's prime minister, claimed that he personally intervened to save Aung San Suu Kyi's life during the massacre, by mobilising his men to bring her to a safe location at a nearby army cantonment.^[4]

In making this statement, the Asian Legal Resource Centre concurs with the preliminary findings of the Ad Hoc Commission on the Depayin Massacre, presented on 25 June 2003. In its summary observations on the attack, the Ad Hoc Commission observed that the attack was clearly premeditated and well organised, as indicated by the following:

1. Up to 5,000 persons were brought to a remote rural location for the purpose of attacking the NLD convoy.
2. The attackers were all well-armed and located strategically at two killing sites.
3. Before the motorcade arrived, local authorities threatened people living in nearby villages to stay indoors.
4. The authorities systematically searched for and arrested survivors of the attack.

The Asian Legal Resource Centre is of the opinion that the massacre at Depayin clearly amounts to a "widespread or systematic attack directed against [a] civilian population, with a knowledge of the attack" (article 7.1 of the Rome Statute of the International Criminal Court) and is therefore a crime against humanity. To date, however, there has been no serious action taken on the massacre.

• List of massacres in Burma