Distemper may refer to:

Look up distemper in Wiktionary, the free dictionary.

• A viral infection
  • Canine distemper, a disease of dogs
  • Feline distemper, a disease of cats
  • Phocine distemper, a disease of seals
• A bacterial infection
  • Equine distemper, or Strangles, a bacterial infection of the horse
• Derangement or disturbance of the four humours or "temper", in pre-modern medicine

• Distemper (paint), a decorative paint and a historical medium for painting pictures
• Distemper (band), a Russian ska punk band
• Distemper (album), by The New Christs
• Remix dystemper, a remix album by Skinny Puppy

• Murrain, a name of any of a number of serious illnesses among cattle and sheep, for which the name 'Distemper' was used in mid 18th century England.

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