Duke of Suffolk was a title that has been created three times in the peerage of England.

The dukedom was first created for William de la Pole, who had already been elevated to the ranks of earl and marquess, and was a powerful figure under Henry VI.

The second creation was for Charles Brandon, a favourite of Henry VIII; his two sons successively inherited the title, but left no more heirs.

The third creation of the dukedom of Suffolk was for Henry Grey, 3rd Marquess of Dorset, in 1551. The duke also held the title Baron Ferrers of Groby (1300). These titles became forfeit when the duke was attainted in 1554.

• Charles Brandon, 1st Duke of Suffolk (1484–1545) was a favourite of Henry VIII
  • Henry Brandon (1516–1522) died at the age of six. Eldest son of the above.
  • Henry Brandon, 1st Earl of Lincoln (1523–1534), second son of the 1st Duke, predeceased his father, without issue. Younger brother of the above.
• Henry Brandon, 2nd Duke of Suffolk (1535–1551), third son of the 1st Duke, died in his youth of sweating sickness. Half-brother of the two Henrys above.
• Charles Brandon, 3rd Duke of Suffolk (1537–1551), fourth son of the 1st Duke, died very shortly after his brother the 2nd Duke also of sweating sickness, and their father's titles became extinct.

Subsidiary titles: Marquess of Dorset (1475), Baron Ferrers of Groby (1300), Baron Harington (1324), Baron Bonville (1449)

• Henry Grey, 1st Duke of Suffolk, 3rd Marquess of Dorset (1517–1554), married to a daughter of the Charles Brandon the previous first Duke of the second creation. He was notable as the father of Lady Jane Grey (de facto Queen of England for nine days). After his attempt to place his daughter on the throne failed, he was pardoned, but after his participation in Wyatt's Rebellion Mary I had him executed for treason in February 1554. His honours were forfeit although, in any case, he had no male issue who would have inherited.

• Earl of Suffolk