East Kilbride, Strathaven and Lesmahagow is a county constituency of the House of Commons of the Parliament of the United Kingdom, which was first used in the general election of 2005. It replaced East Kilbride and some of Clydesdale, and it elects one Member of Parliament (MP) by the first past the post system of election.

Further to the completion of the 2023 Periodic Review of Westminster constituencies, the seat will be subject to boundary changes which will include the loss of Lesmahagow. As a consequence, it will be renamed East Kilbride and Strathaven, to be first contested at the next general election.^[1]

As created by the Fifth Review of the Boundary Commission for Scotland, the constituency covers part of the South Lanarkshire council area. The rest of the council area is covered by the Dumfriesshire, Clydesdale and Tweeddale, Lanark and Hamilton East, and Rutherglen and Hamilton West. constituencies. (the Dumfriesshire, Clydesdale and Tweeddale constituency also covers part of the Dumfries and Galloway council area and part of the Scottish Borders council area).

The terms of the East Kilbride, Strathaven and Lesmahagow name refer to the towns of East Kilbride, Strathaven and Lesmahagow. However, the constituency also includes the settlements of Auldhouse, Blackwood, Caldermill, Chapelton, Drumclog, Glassford, Kirkmuirhill, Jackton, Nerston, Stonehouse and Thorntonhall.

The following electoral wards form the constituency:

• In full: Avondale and Stonehouse, East Kilbride Central North, East Kilbride Central South, East Kilbride East, East Kilbride South, East Kilbride West
• In part: Clydesdale South, Clydesdale West

Until the SNP landslide at the 2015 election, the constituency, and its predecessors East Kilbride, Lanark, and Clydesdale, had been represented continuously by the Labour party since the late 1950s. Following the defection of sitting MP Lisa Cameron in October 2023 from the SNP, the constituency was represented by the Conservative Party for the first time.