Edward Brake Jackson (January 25, 1793 – September 8, 1826) was a U.S. Representative from Virginia, son of George Jackson and brother of John G. Jackson.

Born in Clarksburg, Virginia (now West Virginia), Jackson attended Randolph Academy at Clarksburg. He studied medicine and commenced practice in Clarksburg. During the War of 1812 he was assigned as a surgeon's mate, Third Regular Virginia Militia, at Fort Meigs, Ohio. He served as a member of the State house of delegates 1815–1818. He served as clerk of the United States district court in 1819.

Jackson was elected as a Democratic-Republican to the Sixteenth Congress to fill the vacancy caused by the resignation of James Pindall and reelected to the Seventeenth Congress and served from October 23, 1820, to March 3, 1823. He declined to be a candidate for renomination in 1822. He died at Bedford Springs, near Bedford, Pennsylvania, September 8, 1826. He was interred near Bedford, Pennsylvania.

1821; Jackson won election with 75.22% of the vote, defeating Federalist Thomas Wilson.

• United States Congress. "Edward B. Jackson (id: J000010)". Biographical Directory of the United States Congress.

 This article incorporates public domain material from the Biographical Directory of the United States Congress