The name Edwin means "wealth-friend". It comes from Old English: ēad (wealth, good fortune) and Old English: wine (friend).^[1] Thus the Old English form is Ēadwine, a name widely attested in early medieval England. Edwina is the feminine form of the name.

Notable people and characters with the name include:

• Edwin of Northumbria (died 632 or 633), King of Northumbria and Christian saint
• Edwin (son of Edward the Elder) (died 933)
• Eadwine of Sussex (died 982), Ealdorman of Sussex
• Eadwine of Abingdon (died 990), Abbot of Abingdon
• Edwin, Earl of Mercia (died 1071), brother-in-law of Harold Godwinson (Harold II)
• Edwin Sandys (bishop) (1519–1588), Archbishop of York

• E. W. Abeygunasekera, Sri Lankan Sinhala politician
• Edwin Ariyadasa (1922–2021), Sri Lankan Sinhala journalist
• Edwin Austin Abbey (1852–1911), British artist
• Edwin Eugene Aldrin (born 1930), birth name of Buzz Aldrin, American astronaut
• Edwin Howard Armstrong (1890–1954), American inventor
• Edwin Batdorf (1853–1927), American colonel
• Edwin L. Bauer (1905–c. 1989), American tropical modernist architect in Hawai'i
• Edwin Bennett (potter) (1818–1908), English American pioneer of the pottery industry and art in the United States
• Edwin Bennett (cricketer) (1893–1929), English cricketer
• Edwin Keppel Bennett (1887–1958), English writer, poet, Germanist and academic
• Edwin Biedermann (1877–1929), British real tennis player
• Edwin Birdsong (1941–2019), American keyboardist and organist
• Edwin Booth (1833–1893), American Shakespearean actor
• Edwin H. Brainard (1882–1957), American Marine aviation pioneer
• Edwin Bramall (1923–2019), Chief of the Defence Staff of the British Armed Forces
• Edwin Cassiani (born 1972), Colombian boxer
• Edwin Centeno (1981–2010), Peruvian race walker
• Edwin Chadwick (1800–1890), British social reformer
• Edwin Clarke (1919–1996), British neurologist and medical historian
• Edwin L. Cox, American oilman and philanthropist from Dallas, Texas
• Edwin M. Cronk (1918–2020), American diplomat
• Edwin Davies (1946–2018), British businessman and philanthropist
• Edwin L. Elwood (1847–1907), American soldier
• Edwin Encarnación (born 1983), Dominican baseball player
• Edwin Escobar (born 1992), Venezuelan baseball player
• Edwin L. Felter (1917–2004), justice of the New Mexico Supreme Court
• Edwin Henry Fitler (1825–1896), American businessman and politician
• Edwin E. Floyd (1924–1990), American mathematician
• Edwin M. Gardner (1845–1935), American painter
• Edwin Ghazal (born 1968), also known as Edwin (musician), Canadian musician
• Edwin Goedhart (born 1962), American politician
• Edwin Norman Hartshorn (1835–1901), American politician and educator
• Edwin Haslam (1932–2013), British physical organic chemist
• E. L. B. Hurulle (1919–2009), Sri Lankan Sinhala diplomat, provincial governor
• Edwin N. Hubbell (1815–1897), American politician
• Edwin Hubble (1889–1953), American astronomer
• Edwin Jackson (baseball) (born 1983), American baseball player
• Edwin R. Keedy (1880–1958), American Dean of the University of Pennsylvania Law School
• Edwin Lutyens (1869–1944), British architect
• Edwin McCain (born 1970), American musician
• Edwin Meese (born 1931), American attorney general
• Edwin Moses (born 1955), American hurdler
• Edwin Mosquera (footballer) (born 2001), Canadian footballer
• Edwin Mosquera (weightlifter) (1985–2017), Colombian weightlifter
• Edwin Newman (1919–2010), American newscaster and journalist
• Edwin Olivarez (born 1963), Filipino politician
• Edwin Orozco (born 1982), Colombian road cyclist
• Edwin Alfred Rickards (1872–1920), British architect
• Edwin Spanier (1921–1996), American mathematician
• Edwin Starr (1942–2003), American soul music singer
• Edwin Thomas (disambiguation), multiple people
• Edwin Tsai, Hong Kong former tennis player
• Edwin Tsitsi (1925–1997), Nauruan politician
• Edwin van der Sar (born 1970), Dutch football player
• Edwin Vurens (born 1968), Dutch football player
• Edwin Walker (disambiguation), multiple people
• Ed. Weinberger (born 1945), American screenwriter and television producer
• Edwin Wijeyeratne (1889–1968), Sri Lankan cabinet minister
• Edwin Bidwell Wilson (1879–1964), American mathematician
• Edwin (director) (born 1978), Indonesian filmmaker

• Edwin Drood, main character in The Mystery of Edwin Drood, an unfinished novel by Charles Dickens
• Deputy Edwin Durland, in Gravity Falls, an animated television series
• Edwin Jarvis, a Marvel Comics supporting character
• Aun (known as Edwin the Old in English), mythical Swedish king
• Edwin, a puppet character in Pajanimals, a children's television series