Aikaterini Trikoupi (Greek: Αικατερίνη Τρικούπη, Constantinople, 1800 – Aegina, 15 July 1871) was the wife of the Prime Minister of Greece and historian Spyridon Trikoupis. Her son was Charilaos Trikoupis, also a prime minister.

She was born in Constantinople in 1800, the daughter of the scholar and officer in the Danubian Principalities, Nicholas Al. Mavrokordatos (1744–1818)^[1] and Smaragda Karatza. She had a brother, the fighter of the Greek Revolution of 1821 and later politician of the independent Greek state, Alexandros Mavrokordatos, and two sisters, Eleni and Efrosini (wife of Friedrich Eduard von Rheineck).^[2] Her uncle was the ruler (hospodar) of Wallachia, John Caradja.^[3]

When the Greek Revolution began and the Ottomans started persecutions against the Greeks of Constantinople, her house at Arnavutköy was attacked^[1] while her uncle, Georgios Mavrokordatos, was hanged.^[4] Later, in fear of being captured and ending up in a harem, she left her house and sought refuge with an English priest who helped her to escape. She came to Greece and specifically to Nafplio, where she was reunited with her brother, Alexandros.^[1][5]

On 7 January 1826 she married in Nafplio the politician Spyridon Trikoupis.^[6][7] The marriage produced four children: Aglaïa (1830–1842), Charilaos (1832–1896), Othon (1833–1844) and Sophia (1838–1916).^[8]

She lived for many years abroad, mainly in London, where her husband served as ambassador; later the family settled in Patissia.^[9] She died on 15 July 1871 in the Trikoupis villa in Aegina from drowning.^[10] She was buried in the First Cemetery of Athens in the family tomb of the Trikoupis family.

She was famous for her stature, kindness and education^[1] which she acquired after adulthood, learning among other things, French.^[11] In the National Historical Museum, among the exhibits, there is a wallet of Charilaos Trikoupis which includes a photo of Aikaterini.^[10]