Epigonus of Ambracia (Greek: Ἐπίγονος Ἀμβρακιώτης; fl. 6th century BC) was a Greek musician from Ambracia in South Epirus, who was admitted to a citizenship at Sicyon, where he lived, performed and taught. The epigonion (string instrument) was invented, or at least introduced in Greece by Epigonus. He was a contemporary of Lasus of Hermione.

• Athenaeus iv.183d and xiv, 637f.1.7.
• The Science of Harmonics in Classical Greece by Andrew Barker

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