Ijms-21-05932-g004.webp
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Summary
| Description |
English:
Mild versus severe immune response during SARS-CoV-2 infection. In regards to cytokine signature during SARS-CoV-2, mild and moderate cases showed a controlled response with higher expression of IL-1β, IL-1RA, IL-2RA, IL-6, IL-7, IL-8, IL-9, IL-10, basic FGF, G-CSF, GM-CSF, HGF, IFNγ, IP-10, MCP-1, MIP-1a, MIP-1b, PDGF, TNF-α and VEGF. While, a cytokine-induced immunopathological mechanism has been observed with an increase of IL-2, IL-7, IL-17, IL-10, MCP-1, MIP-1a and TNF-α in severe cases, leading to a bystander effect.
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| Date | |
| Source |
Lebeau, G.; Vagner, D.; Frumence, É.; Ah-Pine, F.; Guillot, X.; Nobécourt, E.; Raffray, L.; Gasque, P. Deciphering SARS-CoV-2 Virologic and Immunologic Features. Int. J. Mol. Sci. 2020, 21, 5932. https://doi.org/10.3390/ijms21165932 |
| Author | Grégorie Lebeau, Damien Vagner, Étienne Frumence, Xavier Guillot, Estelle Nobécourt, Loïc Raffray, and Philippe Gasque |
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