Flavonoid_4'-O-methyltransferase

Flavonoid 4'-O-methyltransferase

Flavonoid 4'-O-methyltransferase

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Flavonoid 4'-O-methyltransferase (EC 2.1.1.231, SOMT-2, 4'-hydroxyisoflavone methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + 4'-hydroxyflavanone S-adenosyl-L-homocysteine + 4'-methoxyflavanone
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The enzyme catalyses the 4'-methylation of naringenin.

References

  1. [1]
    Kim DH, Kim BG, Lee Y, Ryu JY, Lim Y, Hur HG, Ahn JH (September 2005). "Regiospecific methylation of naringenin to ponciretin by soybean O-methyltransferase expressed in Escherichia coli". Journal of Biotechnology. 119 (2): 155–62. doi:10.1016/j.jbiotec.2005.04.004. PMID 15961179.
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