Antigua & Barbuda and Belize are two of fifteen commonwealth realms, members of: the Association of Caribbean States, the Caribbean Community, the Caribbean Development Bank, the Commonwealth of Nations, ECLAC, EU-CARIFORUM, the Organisation of African, Caribbean and Pacific States, the Organization of American States, and the United Nations. Both countries established diplomatic relations on 4 February 1983.^[44]

Antigua & Barbuda and Canada are two of fifteen commonwealth realms, members of: the Commonwealth of Nations, the Organization of American States, and the United Nations. Both countries established diplomatic relations in 1967.^[45][46]

• Antigua and Barbuda is accredited to Canada from its embassy in Washington, D.C., United States and has a consulate-general in Toronto.
• The Canadian High Commission in Bridgetown, Barbados is accredited to Antigua and Barbuda.^[47]

Both countries have established diplomatic relations.^[48]

• Both countries established diplomatic relations on 22 July 2004.^[49]
• Both countries are full members of Commonwealth of Nations.

Denmark is represented in Antigua and Barbuda by its Consulate General in New York and an honorary consulate in St. John's, Antigua and Barbuda.^[50]

• Both countries established diplomatic relations on 3 February 1982.^[51]
• Both countries are full members of Caribbean Community and of Organization of American States.

Both countries have established diplomatic relations and have an Extradition Arrangement.^[52][53]

Ireland is represented in Antigua and Barbuda through its embassy in Washington DC, United States.^[54][55]

Israel is represented in Antigua and Barbuda through its embassy in Dominican Republic.^[56]

• Both countries established diplomatic relations on 23 July 2004.^[57]
• Both countries are full members of Commonwealth of Nations.

• Antigua and Barbuda has a non-resident ambassador accredited to Mexico from its capital in St. John's.^[58]
• Mexico is accredited to Antigua and Barbuda from its embassy in Castries, Saint Lucia and maintains an honorary consulate in St. John's.^[59]

• Both countries have established diplomatic relations.^[60]
• Both countries are full members of Commonwealth of Nations.

• Both countries have established diplomatic relations.^[61]
• Both countries are full members of Commonwealth of Nations.

The establishment of diplomatic relations between the Republic of Korea (South Korea) and Antigua and Barbuda began on 1 November 1981.^[62]

Both countries established diplomatic relations on 27 June 1988.

• Turkish Embassy in Santo Domingo is accredited to Antigua and Barbuda.^[64]
• Trade volume between the two countries was 12.5 million USD in 2019.^[65]

Both countries have established diplomatic relations. Both countries are full members of Commonwealth of Nations.

Relations between Antigua and Barbuda and the United States have been friendly since Antigua and Barbuda's independence from the United Kingdom in 1981.

The United States has supported the Government of Antigua and Barbuda's effort to expand its economic base and to improve its citizens' standard of living. However, concerns over the lack of adequate regulation of the financial services sector prompted the US Government to issue a financial advisory for Antigua and Barbuda in 1999. The advisory was lifted in 2001, but the US Government continues to monitor the Government of Antigua and Barbuda's regulation of financial services.

The United States also has been active in supporting post-hurricane disaster assistance and rehabilitation through the US Agency for International Development's (USAID) Office of Foreign Disaster Assistance and the Peace Corps. US assistance is primarily channelled through multilateral agencies such as the World Bank and the Caribbean Development Bank (CDB), as well as through the USAID office in Bridgetown, Barbados.

Antigua and Barbuda is strategically situated in the Leeward Islands near maritime transport lanes of major importance to the United States. Antigua has long hosted a US military presence. A former US Navy support facility, turned over to the Government of Antigua and Barbuda in 1995, is now being developed as a regional coast guard training facility.

Antigua and Barbuda's location close to the US Virgin Islands and Puerto Rico makes it an attractive transshipment point for narcotics traffickers. To address these problems, the United States and Antigua and Barbuda have signed a series of counter-narcotic and counter-crime treaties and agreements, including a maritime law enforcement agreement (1995), subsequently amended to include overflight and order-to-land provisions (1996); a bilateral extradition treaty (1996); and a mutual legal assistance treaty (1996). In addition, Antigua and Barbuda receives counter-narcotics assistance and benefits from US military exercise-related and humanitarian civic assistance construction projects.

In 2005, Antigua and Barbuda had 239,804 stay-over visitors, with nearly 28% of Antigua and Barbuda's visitors coming from the United States. It is estimated that 4,500 Americans reside in the country.

In 2005 both countries disputed a World Trade Organization ruling over gambling law. In 2007 relations were strained when Antigua and Barbuda demanded sanctions worth $3.4bn imposed on the US for its failure to obey the WTO gambling ruling stating that "while we realise this is a significant step for Antigua and Barbuda to take, we feel we have no choice in the matter".^[66] Nevertheless, relations between the two countries are still strong.

Antigua and Barbuda enjoys close relations with Venezuela. As of June 2009 it became a formal member of the Bolivarian Alliance for the Americas (ALBA) international co-operation organisation and the Caribbean oil alliance Petrocaribe. In 2009 Antigua and Barbuda received US$50 million from Venezuela because of the country's membership of these initiatives.

"We have benefited from these relationships and so we will continue to forge these alliances, whether it is with Venezuela, Cuba or whoever else that we feel is in the interest of Antigua and Barbuda and the sub-region," said the Prime Minister of Antigua and Barbuda Baldwin Spencer.^[67]