Franciscan Health is the name under which the Franciscan Alliance, Inc., a Catholic healthcare system, operates. It operates eleven hospitals serving Indiana and one hospital in Illinois and employs over 18,000 full- and part-time employees. Franciscan Alliance is under the sponsorship of the Sisters of St. Francis of Perpetual Adoration, Inc.

Mother Maria Theresia Bonzel founded the Congregation of the Sisters of St. Francis of Perpetual Adoration in 1863 in Olpe, Germany. Drawn to the ideals of Francis of Assisi, Mother Theresia cared for poor and neglected children and for persons in need of healthcare. In 1875, she sent sisters to Indiana where the mission grew to include hospitals, schools, orphanages and homes for the aged. St. Elizabeth Hospital, now Franciscan Health Lafayette Central in Lafayette, was the first facility founded by the sisters in America.^[1] In 1931 the sisters divided into eastern and western provinces, the eastern centered at Mishawaka, Indiana.

In 1974, the sisters of the eastern province incorporated their healthcare ministry under the name of the "Sisters of St. Francis Health Services, Inc." In 1986, the corporate offices were moved to their current location on the provincialate grounds in Mishawaka.

In November 2010, Sisters of St. Francis Health Services, Inc., changed its name to "Franciscan Alliance, Inc."^[2] In September 2016, Franciscan Alliance renamed its healthcare facilities using “Franciscan Health” and location, rather than the names of saints.^[3]