Fumarate_reductase_(NADH)

Fumarate reductase (NADH)

Fumarate reductase (NADH)

Type of enzyme


In enzymology, a fumarate reductase (NADH) (EC 1.3.1.6) is an enzyme that catalyzes the chemical reaction

succinate + NAD+ fumarate + NADH + H+

Thus, the two substrates of this enzyme are succinate and NAD+, whereas its three products are fumarate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is succinate:NAD+ oxidoreductase. Other names in common use include NADH-fumarate reductase, NADH-dependent fumarate reductase, and fumarate reductase (NADH).


References

    • Hopgood MF, Walker DJ (1969). "Succinic acid production by rumen bacteria. III. Enzymic studies on the formation of succinate by Ruminococcus flavefaciens". Aust. J. Biol. Sci. 22: 1413–1424.



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