Furoquinoline
Furoquinoline alkaloid
Group of chemical compounds
Furoquinoline alkaloids are a group of alkaloids with simple structure. Distribution of this group of alkaloids is essentially limited to plant family Rutaceae. The simplest member of this group is dictamnine and most widespread member is skimmianine.[1]
A furoquinoline alkaloid, dictamnine, is very common within the family Rutaceae. It is the main alkaloid in the roots of Dictamnus albus and responsible for the mutagenicity of the drug derived from crude extracts.[2] Dictamnine was also reported to be a phototoxic and photomutagenic compound.[3] It participates in the severe skin phototoxicity of the plant.[4] Another furoquinoline alkaloid, skimmianine, has strong antiacetylcholinesterase activity.[5]