The globose nucleus is one of the deep cerebellar nuclei. It is located medial to the emboliform nucleus, and lateral to the fastigial nucleus. The globose nucleus and emboliform nucleus are known collectively as the interposed nuclei.^[1]

The globose nucleus is part of a neural circuit giving rise to descending motor tracts involved in motor control of distal musculature of the upper and lower limbs.^[1]

This nucleus contains primarily large and small multipolar neurons.^{[citation needed]}