Glyceraldehyde-3-phosphate_dehydrogenase_(NAD(P)+)
In enzymology, a glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (EC 1.2.1.59) is an enzyme that catalyzes the chemical reaction
- D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+
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The 4 substrates of this enzyme are D-glyceraldehyde 3-phosphate, phosphate, NAD+, and NADP+, whereas its 4 products are 3-phospho-D-glyceroyl phosphate, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-glyceraldehyde 3-phosphate:NAD(P)+ oxidoreductase (phosphorylating). Other names in common use include (phosphorylating), triosephosphate dehydrogenase (NAD(P)), and glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating).