In enzymology, a glycyrrhizinate β-glucuronidase (EC 3.2.1.128) is an enzyme that catalyzes the chemical reaction

glycyrrhizinate + H₂O ${\displaystyle \rightleftharpoons }$ 1,2-β-D-glucuronosyl-D-glucuronate + glycyrrhetinate

It belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name is glycyrrhizinate glucuronosylhydrolase. Other names in common use include glycyrrhizin β-hydrolase, glycyrrhizin hydrolase, and glycyrrhizinic acid hydrolase.

• α-Glucuronidase
• β-Glucuronidase
• Glucuronosyl-disulfoglucosamine glucuronidase