Goulard's_Extract

Basic lead acetate

Basic lead acetate

Chemical compound


Basic lead acetate, also known as subacetate of lead, is the inorganic compound with the formula Pb3(OH)4(O2CCH3)2. A white solid, it is one of several lead acetates.[1]

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History

Goulard's extract is a solution of lead(II) acetate[2] and lead(II) oxide used as an astringent[3] during the 18th, 19th and early 20th centuries. It was named after its introducer, Thomas Goulard. Lead poisoning and the development of more effective astringents caused doctors to abandon its use. Synonymous or very closely related formulations were known as liquor plumbi subacetis dilutus,[4] eau de Goulard, extract of Saturn, vinegar of Saturn, and liquid acetate of lead. The white water eau de Saturne differed from eau de Goulard in not containing alcohol, but was often confused with it.[5] Goulard's Extract was a primary ingredient in both Goulard's Cerate and Goulard's Water.


References

  1. Carr, Dodd S. (2005). "Lead Compounds". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a15_249. ISBN 978-3527306732.
  2. Thomson, Thomas (1810). A System of Chemistry. London: Bell & Bradfute. pp. v. 3, p. 275. Goulard's Extract.
  3. Pereira, Jon. (1836-05-28). "Materia Medica, or Pharmacology, and General Therapeutics". London Medical Gazette. 18: 314. Retrieved 2008-02-25.
  4. Robley Dunglison (1874). A dictionary of medical science. Henry C. Lea. p. 336.
  5. Hermann Pidoux (1880). Treatise on therapeutics. Vol. 1.

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