Granule-cell–Purkinje-cell_synapse

Granule-cell–Purkinje-cell synapse

Granule-cell–Purkinje-cell synapse

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Granule-cell to Purkinje-cell synapses or gcPc synapses are the junctions that form the synapse in the cerebellum between granule cells and Purkinje cells.[1] These synapses are thought to be a storage site for the information that is required for motor coordination and their misfunctioning is involved with some movement disorders.[2] Glutamate is the neurotransmitter.

Purkinje cells (A) and granule cells (B) from a pigeon cerebellum

References

  1. [1]
    "A Wavelet Approach for the Identification of Axonal Synaptic Varicosities from Microscope Images". Retrieved 2010-08-12. The cerebellar parallel fiber system contains the synapses be- tween the granule cells and the Purkinje cells (gcPc synapses), which have a strategic role in cerebellar function
  2. [2]
    Isope, P.; Barbour, B. (November 2002). "Properties of unitary granule cell-->Purkinje cell synapses in adult rat cerebellar slices". Journal of Neuroscience. 22 (22): 9668–78. doi:10.1523/JNEUROSCI.22-22-09668.2002. PMC 6757845. PMID 12427822.
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