Hairy_(gene)

Hairy RNA localisation element (HLE)

Hairy RNA localisation element (HLE)

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The hairy localisation element (HLE) is an RNA element found in the 3' UTR of the hairy gene. HLE contains two stem-loops. HLE is essential for the mediation of apical localisation and the two stem-loop structures act to allow the recognition of hairy mRNA by the localisation machinery.[1] HLE is found in Drosophila species.

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References

  1. [1]
    Bullock SL, Zicha D, Ish-Horowicz D (May 2003). "The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport". The EMBO Journal. 22 (10): 2484–2494. doi:10.1093/emboj/cdg230. PMC 155988. PMID 12743042.
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