Henrietta Catharina, Baroness von Gersdorff (maiden name von Friesen auf Roetha; 6 October 1648 – 6 March 1726) was a German noblewoman, Baroque religious poet, an advocate of Pietism and also a supporter of the beginnings of the Moravian Church. She was the maternal grandmother of Nicolas Ludwig, Count von Zinzendorf.

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She was born in Sulzbach, Upper Palatinate, the daughter of Karl, Baron von Friesen, and Justina Sophia von Raben. She was educated in Dresden and Leipzig. She was a sister of Otto Heinrich von Friesen, chancellor to Saxon Elector Friedrich August I (August der Starke or Augustus the Strong). Unlike most girls of the time, she was trained in multiple disciplines, and even as a youth she was recognized by her contemporaries for her German and Latin verses. She early became a correspondent with many theologians and scientists of the day.

At the age of 24. in 1672, she married Nicolas, Baron von Gersdorff (1629–1702), governor of the Saxon Upper Lusatia.^[1] In that capacity she was able to exercise a not unimportant influence in affairs of both church and state. She supported the movement called Pietism and the Saxon Court preacher Philipp Jakob Spener.

She encouraged the translation of the Bible into the Lusatian Slavic language of Sorbian but also encouraged the schooling of girls. In this connection she was engaged also in the founding of the Magdalenenstift School for girls in Altenburg.^{[citation needed]}

Following her husband's death in 1702, she withdrew to her Grosshennersdorf estate in the mountains of eastern Saxony,^[1] where she died. There she devoted herself to the education of her grandson Nicolas Ludwig, Count von Zinzendorf. Her home was open to many visitors including Lutheran missionaries to Tranquebar and Greenland. She often offered refuge to religious refugees escaping persecution in neighboring Bohemia and Moravia. The German Pietist poet Johann Jakob Rambach considered her spiritual poetry among the best of their day. Some of her verses are still used in the German Moravian Church, and some were set to music by German composer Pauline Volkstein.