Hispanophobia (from Latin Hispanus, "Spanish" and Greek φοβία (phobia), "fear") or anti-Spanish sentiment is a fear, distrust, hatred of; aversion to, or discrimination against the Spanish language, Hispanic, Latino and/or Spanish people, and/or Hispanic culture. The historical phenomenon has had three main stages by originating in 16th-century Europe, reawakening during 19th-century disputes over Spanish and Mexican territory such as the Spanish–American War and the Mexican–American War, and finally in tandem with politically-charged controversies such as bilingual education and illegal immigration to the United States.

In Spain, the complex of identity politics has also identified Catalan, Basque, and Galician nationalism with hispanophobic views and discourse.