Incantesimo (English: Enchantment) is a long-running Italian drama series, originally broadcast on the RAI network from 1998 to 2008. It is mainly set in a hospital called Clinica Life in Rome, Italy, and revolves around the lives of the staff that works in it. It is known for having different lead actors who play a different story in almost every of its ten seasons.

Incantesimo originally premiered in June 1998, on the Italian Rai 2 channel as an alternative prime time programming to the 1998 FIFA World Cup, which was running at the same time on Rai 1. The plot is written by popular Italian writer Maria Venturi. Gianni Lepre directed the series. The main characters are played by Agnese Nano, Vanni Corbellini and Giovanni Guidelli. The actress Daniela Poggi, who plays the malicious Cristina Ansaldi – one of the most notable characters – was personally called by Gianni Lepre to join the cast as he thought she's perfect for the role.

Surprisingly, the first season was very successful, attracting more than 4 million viewers during the broadcasting of its 10 episodes.

In Romania, the series was broadcast on TVR Timişoara