The inferior parietal lobule (subparietal district) lies below the horizontal portion of the intraparietal sulcus, and behind the lower part of the postcentral sulcus. Also known as Geschwind's territory after Norman Geschwind, an American neurologist, who in the early 1960s recognised its importance.^[1] It is a part of the parietal lobe.

It is divided from rostral to caudal into two gyri:

• One, the supramarginal gyrus (BA 40), arches over the upturned end of the lateral fissure; it is continuous in front with the postcentral gyrus, and behind with the superior temporal gyrus.
• The second, the angular gyrus (BA 39), arches over the posterior end of the superior temporal sulcus, behind which it is continuous with the middle temporal gyrus.

In males, the inferior parietal lobule is significantly more voluminous in the left hemisphere compared to the right. This extreme asymmetry is not present in females, and may contribute to slight cognitive variations of both sexes.^[2]

In macaque neuroanatomy, this region is often divided into caudal and rostral portions, cIPL and rIPL, respectively. The cIPL is further divided into areas Opt and PG whereas rIPL is divided into PFG and PF areas.^[3]

Inferior parietal lobule has been involved in the perception of emotions in facial stimuli,^[4] and interpretation of sensory information. The Inferior parietal lobule is concerned with language, mathematical operations, and body image, particularly the supramarginal gyrus and the angular gyrus.^[5]

Destruction to the inferior parietal lobule of the dominant hemisphere results in Gerstmann's syndrome: right-to-left confusion, finger agnosia, dysgraphia and dyslexia, dyscalculia, contralateral hemianopia, or lower quadrantanopia. Destruction to the inferior parietal lobule of the non-dominant hemisphere results in topographic memory loss, anosognosia, construction apraxia, dressing apraxia, contralateral hemispatial neglect, contralateral hemianopia, or lower quadrantanopia.

Functional imaging experiments suggest that the left anterior supramarginal gyrus (aSMG) of the human inferior parietal lobule exhibits an evolved specialization related to tool use. It is not currently known if this functional specialization is unique to humans as complementary experiments have only been performed with macaque monkeys and not apes. The habitual use of tools by chimpanzees makes the uniqueness of the human aSMG an open question as its function may have evolved prior to the split from our last common ancestor.^[6]

• Temporoparietal junction