Ion Mitilineu (28 September 1868 – 11 June 1946)^[1][2] was a Romanian diplomat who served as the Minister of Foreign Affairs of Romania in 1926–1927.^[3]

Mitilineu was appointed the Minister of Foreign Affairs of Romania on March 30, 1926, when Alexandru Averescu took the office of Prime Minister of Romania.^[4] Mitilineu was a part of Romanian diplomatic advance in efforts to reestablish good relations with European states and sign military cooperation agreements with neighbors. Prime Minister Averescu had already met with the Italian leader Benito Mussolini in 1924 and was interested in close cooperation with Italy. During Mitilineu's term in office, Romanian-Italian relations significantly improved and in September 1926, friendship treaty between two states was signed. After that Romania also signed the Locarno Pact.^[5]

Mitilineu also developed good relations Czechoslovakia and Yugoslavia through the Little Entente alliance against potential irredentist threats from Hungary.^[6] He is considered one of the most successful foreign ministers of Romania. In domestic politics, he also tried to unify the Peasant's Party to create an anti-Liberal bloc in Romania.^[7]

Mitilineu died on 11 June 1946, aged 77.

• Little Entente
• Foreign relations of Romania