Isola is the surname of the following people

• Akinwunmi Isola, Nigerian playwright, actor, dramatist, culture activist and scholar
• Albert Isola, Gibraltarian politician
• Amédée Isola (1898–1991), French runner
• Andrés Isola (born 1974), Olympic windsurfer from Uruguay
• Antonia Isola (1876–?), pseudonym of American writer Mabel Earl McGinnis
• Émile Isola (1860–1945), French conjurer and theatre director
• Floris Isola (born 1991), French association football player
• Frank Isola (1925–2004), American jazz drummer
• Frank Isola (sportswriter), American sportswriter
• Johnny Dell Isola (1912–1986), American football player
• Maija Isola (1927–2001), Finnish textile designer
• Peter Isola (1929—2006), Gibraltarian politician and lawyer, father of Albert
• Paul Isola, Gibraltarian musician and songwriter
• Vincent Isola (1862–1947), French conjurer and theatre director, brother of Émile

This page lists people with the surname Isola.
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