2014 NFL Combine

Seattle Seahawks

Jeffcoat was originally predicted to be drafted somewhere in the middle rounds of the 2014 NFL Draft. However, neither he nor any other member of the Longhorns team was drafted that year, the first time since 1937 that no Longhorns were drafted.^[7] Jeffcoat signed with the Seattle Seahawks as an undrafted free agent. The Seahawks released him on August 25, 2014.^[8]

Washington Redskins

On September 2, 2014, Jeffcoat was signed to the practice squad of the Washington Redskins.^[9] He was promoted to the active roster on October 7,^[10] but was waived three days later. The Redskins re-signed him to their practice squad again on November 13.^[11] He was promoted again to the active roster on December 16.^[12] In the Week 16 win against the Philadelphia Eagles that removed them from playoff contention, Jeffcoat recorded his first career sack on quarterback Mark Sanchez.^[13] The following week, he had his first career start with Trent Murphy on injured reserve and recorded his first career interception, which came off Tony Romo, in the Week 17 loss to the Dallas Cowboys.^[14]

On November 7, 2015, he was placed on the team's injured reserve.^[15] He was waived by the team on April 14, 2016.^[16]

Cleveland Browns

Jeffcoat was claimed off waivers by the Cleveland Browns on April 15, 2016.^[17] On August 1, 2016, Jeffcoat was waived by the Browns.^[18]

Winnipeg Blue Bombers

Jeffcoat was signed by the Winnipeg Blue Bombers (CFL) on February 21, 2017.^[19] In 16 games played, Jeffcoat contributed 36 tackles, 7 sacks, 3 tackles on special teams, one interception, and a forced fumble. In Winnipeg's one postseason game, Jeffcoat had 5 tackles and a sack, but the Blue Bombers were defeated by Edmonton. 2018 saw Jeffcoat miss several games with injury, but he still put up a respectable 21 tackles, 5 sacks, and 2 forced fumbles. Jeffcoat also had a monster postseason, with four sacks in two games played, but a loss to Calgary in the Western Division final denied Jeffcoat and the Blue Bombers a trip to the 106th Grey Cup.

After fulfilling his CFL rookie contract, Jeffcoat was eligible to become a free agent on February 12, 2019. Jeffcoat was pursued by interested NFL teams, and was brought in for a workout by the Cincinnati Bengals.^[20] However, Jeffcoat was signed to a two year contract extension with the Blue Bombers on January 21, 2019.^[21] Jeffcoat's 2019 season was almost identical to his 2018; he missed time with injury, played in the same number of games, had the same number of sacks and forced fumbles. In the 2019 Grey Cup, Jeffcoat had 4 tackles, 2 sacks and forced a fumble, which he recovered as the Blue Bombers went on to win 33-12.^[22]

Jeffcoat signed a one-year contract extension with the Blue Bombers on January 8, 2021.^[23] He played in 12 regular season games for the Bombers during the 2021 season and set a career high with nine quarterback sacks and four forced fumbles, to go along with 26 defensive tackles. Jeffcoat was named a CFL All-Star for the first time in his career, as he helped the Bombers win consecutive Grey Cups. Jeffcoat missed two games in the 2022 season with a hip injury.^[24]

On January 19, 2023, Jeffcoat and the Bombers agreed to a one-year contract extension.^[25] Jeffcoat suffered a lower-body injury in the Bombers' Week 1 win, the injury caused him to miss some action at the start of the season.^[26] However, Jeffcoat recovered and played in the most games in a single season since his rookie year, and produced his second highest numbers of sacks and forced fumbles on the year. After not hearing much from the Bombers prior to free agency, Jeffcoat retired on February 9.^[27]

CFL