Seattle Seahawks (first stint)

On April 29, 2016, Reed was drafted in the second round of the 2016 NFL Draft with the 49th overall selection by the Seattle Seahawks after the team traded their second-, and fourth-round picks (56th, and 124th overall) to the Chicago Bears in order to move up to #49 in order to select Reed.^[13] On May 5, 2016, Reed signed a 4-year deal worth $4.889 million overall with a $1.756 million bonus.^[14]

As a rookie in 2016, Reed played 15 games and finished the year with 34 tackles, 1.5 sacks, and three passes defended. He finished his second season in 2017 with 45 tackles, 1.5 sacks and 4 tackles for loss.

In 2018, Reed had a breakout year. He had a career-high 2 sacks in a Week 3 win over the Dallas Cowboys, then matched his production from the previous two years in just four games with another sack the following week. He finished the season with 5 sacks in his final 5 games, to bring his season total up to 10.5 sacks.^{[citation needed]}

Reed was suspended the first six games of the 2019 season for a violation of the personal conduct policy for an incident from early 2017.^[15] After the Seahawks traded for Jadeveon Clowney, Reed changed his number to 91. Reed was reinstated from suspension on October 14, 2019, and was activated to the active roster prior to Week 7.^[16]

On March 16, 2020, Reed signed a two-year, $23 million contract extension with the Seahawks.^[17] In Week 9 against the Buffalo Bills, Reed sacked quarterback Josh Allen 2.5 times during the 44–34 loss.^[18] In the Wild Card Round of the playoffs against the Los Angeles Rams, Reed sacked Jared Goff two times during the 30–20 loss.^[19] Reed was released after the season on March 26, 2021.^[20]

Kansas City Chiefs

Reed signed a one-year, $5 million deal with the Kansas City Chiefs on March 31, 2021, with performance incentives to increase his potential pay up to $7 million.^[21][22] He started all 17 games in 2021, recording 43 tackles, 2.5 sacks, and two forced fumbles.

Green Bay Packers

Reed signed a one-year, $3.25 million deal with the Green Bay Packers on March 23, 2022.^[23][24] The contract included incentives for Reed to increase his salary up to $4.5 million, and had void years to spread the cap charge of his $1.865 million signing bonus over the next four years.^[25]

Seattle Seahawks (second stint)

On March 16, 2023, Reed signed a two-year, $12.8 million contract to return to the Seahawks.^[26]

Regular season

Postseason