Florida Panthers (2013–2022)

On September 20, 2011, playing in his second NHL pre-season game for the Florida Panthers, Huberdeau scored a goal against the Nashville Predators. He played five pre-season games with the Panthers, tallying three goals and one assist to lead the team in pre-season scoring before being sent back to Saint John on October 3.

Following the conclusion of the 2012–13 NHL lockout, Huberdeau made the Panthers starting roster for the 2012–13 season. He scored his first NHL goal on January 19, 2013, against Cam Ward of the Carolina Hurricanes on the second shift and first shot of his NHL career. Huberdeau would add two assists in the 5–1 victory to earn the first star of the game in his NHL debut. NHL regulations allowed the Panthers to keep Huberdeau in their lineup for a maximum of five games before they could either return him to his junior team or keep him in Florida. On January 28, 2013, after registering a goal and two assists in five games, the Panthers announced Huberdeau would remain with the Panthers for the remainder of the NHL season.^[11] As a result of his outstanding rookie season, Huberdeau won the 2013 Calder Memorial Trophy.^[12]

In the 2014–15 season, Huberdeau scored a career-high 15 goals and 39 assists (54 points) in 77 games played. After Florida's late-season acquisition of forward Jaromír Jágr from the New Jersey Devils, who was placed on Florida's top line alongside Huberdeau and Aleksander Barkov, Huberdeau recorded 6 goals and 15 assists (21 points) in 20 games played to finish the season.^[13] Huberdeau's assists total (39) was the most for a Panther since Stephen Weiss in 2008–09. At the conclusion of the season, Huberdeau was set to become a restricted free agent.

On September 6, 2016, the Panthers signed Huberdeau to a six-year, $35.4 million contract averaging $5.9 million per season. Panthers president of hockey operations Dale Tallon spoke very highly of Huberdeau after the signing, saying, "Jonathan is a highly talented and dynamic player who is another important piece of our team's young core. In each of his last two seasons, he has posted over 50 points and has developed into a key component of our team's offense."^[14]

On November 16, 2019, Huberdeau surpassed Stephen Weiss to become the all-time leader for the Florida Panthers in assists.

On April 1, 2022, Huberdeau picked up his 71st assist in the Panthers' 4–0 win over the Chicago Blackhawks. In doing so, he surpassed Joé Juneau's previous NHL record (70) for most assists in a single season by a left-winger.

On April 5, 2022, Huberdeau became the first Panthers player to reach 100 points in a season in the Panthers' 7–6 comeback win against the Toronto Maple Leafs, with Huberdeau scoring the overtime goal.

Calgary Flames (2022–present)

On July 22, 2022, Huberdeau, along with MacKenzie Weegar, Cole Schwindt, and a 2025 conditional first-round draft pick, were traded to the Calgary Flames for Matthew Tkachuk and a conditional fourth-round draft pick.^[15] On August 3, Huberdeau signed an eight-year, $84 million contract extension with the Flames, carrying an average annual value of $10.5 million.^[16] It was the largest contract in Flames' franchise history, surpassing Sean Monahan's $44.625 million contract signed in 2016.

Huberdeau's point production during the 2022–23 season took a significant dip from his previous season with the Florida Panthers, setting an NHL record for the biggest point drop off in NHL history between seasons; falling from 115 points in 2021–22, to 55 points the next season – his lowest points production for a full season since 2014–15.^{[lower-alpha 1][17]}